Metformin, is a widely used diabetes drug and is often the first-line treatment after a patient is diagnosed. Now a study in macaques, shows that it can do much more than just control diabetes.
In a 40 month long study conducted by researchers in China, 13 to 16 year old male macaques, which is equivalent to middle age for humans were given daily doses of metformin to study the effect of this drug on aging. Remarkably, it slowed down liver aging and aging of the brain. Aging of the frontal lobe of the brain slowed down by an average of 6 years. The research team has now launched a human clinical trial to study whether similar slowing of brain aging also happens in humans.
Reference:
https://www.nature.com/articles/d41586-024-02938-w
https://www.cell.com/cell/abstract/S0092-8674(24)00914-0
https://www.sciencealert.com/common-diabetes-medication-slows-brain-aging-in-monkeys
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